Identification

Title

Antiviral, antibiotics and decongestants in wastewater treatment plants and receiving rivers in the Thames catchment

Abstract

This dataset contains the concentration of eleven antibiotics (trimethoprim, oxytetracycline, ciprofloxacin, azithromycin, cefotaxime, doxycycline, sulfamethoxazole, erythromycin, clarithromycin, ofloxacin, norfloxacin), three decongestants (naphazoline, oxymetazoline, xylometazoline) and the antiviral drug oseltamivir's active metabolite, oseltamivir carboxylate, measured at 21 locations within the River Thames catchment in England. The measurements were taken weekly during November 2009, once in March 2010 and once in May 2011, with the aim to quantify pharmaceutical usage during the influenza pandemic of 2009 and how this compares to inter-pandemic drug use. River samples were acquired by grab samples in glass jars and analysed by liquid chromatography tandem mass spectrometry (LC MS). Two wastewater treatment plants (WWTPs) in southern England (Benson and Oxford) were also sampled during the peak of the second wave of the 2009 influenza A[H1N1]pdm09 pandemic (10-11 November 2009) and on 15 May 2011 using an automated sampler set to acquired hourly (time proportional) samples from the influent and effluent of the WWTPs. The WWTPs are the source for all the drugs found in the river, hence, these were studied to understand the differential fate of the analytes in the two very different WWTPs. Flows for the WWTP and River sampling locations are presented for each of the sampling times to allow for determining hourly loads for the WWTP and daily loads for the river. Full details about this dataset can be found at https://doi.org/10.5285/8af983e4-e97d-4c07-a34d-753243fa283b

Resource type

dataset

Resource locator

https://data-package.ceh.ac.uk/data/8af983e4-e97d-4c07-a34d-753243fa283b

name: Download the data

description: Download a copy of this data

function: download

https://data-package.ceh.ac.uk/sd/8af983e4-e97d-4c07-a34d-753243fa283b.zip

name: Supporting information

description: Supporting information available to assist in re-use of this dataset.

function: information

Unique resource identifier

code

1406898956642

codeSpace

CEH:EIDC:

Dataset language

eng

Spatial reference system

code identifying the spatial reference system

Classification of spatial data and services

Topic category

inlandWaters

Keywords

Keyword set

keyword value

Hydrography

originating controlled vocabulary

title

GEMET - INSPIRE themes, version 1.0

reference date

date type

publication

effective date

2008-06-01

Keyword set

keyword value

pandemic

influenza

antibiotic

antiviral

decongestant

wastewater treatment plant

river

River Thames

wastewater epidemiology

Benson Sewage Works

Oxford Sewage Works

River Thames catchment (UK)

Geographic location

West bounding longitude

-2.013

East bounding longitude

-0.31

North bounding latitude

52.113

South bounding latitude

51.217

Temporal reference

Temporal extent

Begin position

2009-11-11

End position

2011-05-11

Dataset reference date

date type

publication

effective date

2014-08-01

date type

creation

effective date

2009-11-03

Frequency of update

notPlanned

Quality and validity

Lineage

The sampling of all analytes in the Benson and Oxford WWTP was performed during a 24-hour period spanning 10-11 November 2009. An additional 24-h sampling was initiated on May 15, 2011 from only the Benson WWTP effluent. An automated sampler was used to recover a time-proportional sample (approximately 750 ml) of influent and effluent every hour for 24 hours. Samples were aliquoted into triplicate 50-ml borosilicate glass vials with PTFE-lined caps and immediately stored at -80°C until analysis. Grab samples were acquired from the main river flow at 21 locations within the Thames catchment as part of the CEH Thames Initiative Research Platform on November 3, 11, 17, and 24, 2009, as well as on March 15, 2010 (late-pandemic period) and May 11, 2011 (inter-pandemic period). River flow data was acquired from the National River Flow Archive (http://www.ceh.ac.uk/data/nrfa/) for all locations at the closest gauging station to the sampling site. Samples were transported from the field to the laboratory in amber glass jars (250 ml) within siz hours and transferred into 50-ml borosilicate glass vials with PTFE-lined caps, in triplicate. The samples were stored at -80°C until analysis. An on-line solid phase liquid extraction/liquid chromatography-tandem mass-spectrometry (SPE/LC-MS/MS) method was used to measure the analyte levels in pre-filtered and acidified 1 mL-samples. This on-line SPE/LC-MS/MS method used has 132 been evaluated and described in detail previously: Khan GA, Lindberg R, Grabic R, Fick J (2012) The development and application of a system for simultaneously determining anti-infectives and nasal decongestants using on-line solid- phase extraction and liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal 66: 24-32.

Conformity

Conformity report

specification

title

Commission Regulation (EU) No 1089/2010 of 23 November 2010 implementing Directive 2007/2/EC of the European Parliament and of the Council as regards interoperability of spatial data sets and services

reference date

date type

publication

effective date

2010-12-08

degree

explanation

Data format

name of format

Comma-separated values (CSV)

version of format

Constraints related to access and use

Constraint set

Limitations on public access

Constraint set

Limitations on public access

Constraint set

Limitations on public access

© UK Centre for Ecology & Hydrology

Constraint set

Limitations on public access

If you reuse this data, you should cite: Singer, A.C., Järhult,, J.D., Grabic, R., Khan, G.A., Lindberg, R.H., Fedorova, G., Fick, J., Bowes, M.J., Olsen, B., Söderström, H. (2014). Antiviral, antibiotics and decongestants in wastewater treatment plants and receiving rivers in the Thames catchment. NERC Environmental Information Data Centre https://doi.org/10.5285/8af983e4-e97d-4c07-a34d-753243fa283b

Responsible organisations

Responsible party

organisation name

UK Centre for Ecology & Hydrology

email address

enquiries@ceh.ac.uk

responsible party role

pointOfContact

Responsible party

organisation name

Centre for Ecology & Hydrology

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

Uppsala University

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

University of South Bohemia in Ceske Budejovice

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

Umeå University

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

Umeå University

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

University of South Bohemia in Ceske Budejovice

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

Umeå University

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

Centre for Ecology & Hydrology

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

Uppsala University

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

Umeå University

email address

enquiries@ceh.ac.uk

responsible party role

author

Responsible party

organisation name

NERC EDS Environmental Information Data Centre

email address

info@eidc.ac.uk

responsible party role

custodian

Responsible party

organisation name

NERC Environmental Information Data Centre

email address

info@eidc.ac.uk

responsible party role

publisher

Responsible party

organisation name

UK Centre for Ecology & Hydrology

email address

enquiries@ceh.ac.uk

responsible party role

owner

Metadata on metadata

Metadata point of contact

organisation name

Environmental Information Data Centre

full postal address

Lancaster Environment Centre, Library Avenue, Bailrigg

Lancaster

LA1 4AP

UK

email address

info@eidc.ac.uk

responsible party role

pointOfContact

Metadata date

2021-06-25T18:39:31

Metadata language

eng